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Protein complex production

Many proteins only work together: paired formats, enzyme complexes, multi-subunit targets. 
De Novo design of protein complexes carries to many failure modes to produce with expensive strain engineering.

Lysa unlocks this molecule class by offering co-expressed De Novo production at a price worth the attempt. 

In development Talk to us
SUBUNIT ASUBUNIT BSUBUNIT CONE EXTRACTCo-expressed togetherASSEMBLEDCOMPLEX

Subunits made together in one extract, not built separately and reassembled.

Why complexes are different

Today
Each subunit separately, then hope

Conventional routes build every subunit in its own strain and rely on reassembly afterwards. Ratios, folding and purity all become hand work — and every design round pays for it again.

With Lysa
Co-expression on one process

Subunits are made together in the same extract, on the same cell-free process that serves the whole pipeline. Complexes go through the same loop as any single protein — with the same weekly turnaround.

Bring us a complex

Tell us the components, the assembly you are after and the stage your designs are at.